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Students Using Provigil to Boost Performance

A growing number of students and academics are using “smart drugs” bought over the internet to improve their performance in exams, a senior drug adviser has warned.

Barbara Sahakian, professor of clinical neuropsychology at the University of Cambridge, said British students are buying prescription drugs such as modafinil and Ritalin from suppliers as far afield as India.

One in 10 Cambridge undergraduates has used cognitive-enhancing drugs – while another third said they would use them if they had access to them, a recent survey showed.

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Treating Narcolepsy with Provigil

Provigil is a relatively new prescription drug that is used to treat such sleep disorders as narcolepsy, shift work disorder, and obstructive sleep apnea (OSA). This drug, manufactured by Cephalon, is approved by the U.S. Food and Drug Administration to treat excessive daytime sleepiness caused by these various sleep disorders.

At this point in time, Provigil is only approved for use in adults. It has gained much attention and popularity due to the fact that it is supposed to be a “wakefulness promoting agent” as opposed to a typical “stimulant”.
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Provigil for Fatigue

Provigil, like many drugs that we take for MS symptoms, seems to have a “we’re not sure how it works, but it does” factor. It is widely assumed that the drug works on one of the neurotransmitters (dopamine) in affecting fatigue.

Most of us know very well that these neurotransmitter chemicals live between our axons or nerve endings. They are the substance through which nerve firings occur. We also know that some of our damaged axons do not fire strongly enough to pass signals to the next due to demyelination.

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Provigil: Abuse Potential

Provigil has been thought to produce its wake-promoting effects independent of dopaminergic actions, Dr. Volkow said. Although the Physician’s Desk Reference does suggest there are some dopaminergic effects, including psychoactive and euphoric effects, she noted, “this was dismissed on the fact that the affinity of Provigil Generic for the dopamine transporter was very low.”

However, a series of animal studies, particularly in knockout mice, have suggested that the dopaminergic system might after all be crucial to the alerting properties of Provigil Generic. For example, knockout mice for the dopamine transporter do not respond to Provigil Generic, she noted.

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