Provigil has been used for the treatment of post-chemotherapy cognitive impairment ( off-label). it is also known as a “chemo-brain”.

A number of studies have confirmed that Provigil helps reduce the problems with memory and attention, so scientists were hoping that Provigil might help breast cancer patients, who experience chemo-brain. In another study done on 68 patients it has been proven, that Provigil can help with memory problems in cancer patients.