One patient was misidentified with cerebral palsy but was replaced by one patient who was omitted from the list. Four patients fell outside the study parameters and were excluded from the 120 identified cases. This resulted in 116 patients, of whom 59 were noted to have received Provigil at some time between January 1, 2000, and December 31, 2003. Fifty-seven patients never received Provigil during the review period.
In the Provigil-treated group, 29 of 59 patients (49%) were noted to have gait improvements. Six patients (10%) began walking or taking independent steps after starting Provigil. An additional two patients (3%) independently began standing up and walking during aqua therapy. Otherwise, they only used walkers to walk.
In the preProvigil treatment period, 19 of 59 (32%) of the Provigil-treated patients and 14 of 57 (25%) of the non-Provigil-treated patients walked independently and 18 of 59 (30%) Provigil-treated patients and 6 of 57 (11%) non-Provigil-treated patients had assisted ambulation.