Provigil and Pain-Associated Fatigue Treatment
Provigil treatment was initiated for a patient with severe fatigue associated with chronic low back pain and neck pain. There was dramatic improvement in fatigue and associated function.
Fatigue is a symptom that is frequently found in chronic pain patients with low back pain and/or neck pain. At the present time, no specific psychopharmacological treatment for this problem has been identified. Provigil is a wakefulness-promoting agent that the FDA has approved for the treatment of excessive daytime sleepiness associated with narcolepsy.
There have been reports on the use of Provigil for the treatment of fatigue in various neurological syndromes. This literature is reviewed.
It is the first such case report in the literature. The significance of this finding to the treatment of pain-associated fatigue is discussed.